A study on cancer pain and sleep parameters of cancer patıents: Hydromorphone Hydrochloride

Authors

  • Hayriye Baltaoğlu Alp Necmettin Erbakan University

Keywords:

Cancer Pain, sleep, opioid

Abstract

The ratio of painless sleep was 80% in our study.

26 (52%) of the patients showed no side effects, while 10 (20%) had nausea and 6 (12%) had constipation. 8 (16%) of the patients were found to have other side effects. The frequency of those side effects was nausea, constipation, dizziness, vomiting, respiratory failure and diarrhea respectively.[table 4]

Hydromorphone hydrochloride helped to eliminate sleep disorder, shortness of breath and snoring and relatively improved amount of sleep and adequacy of sleep. It was found that 90% of our patients were able to fall asleep in 1-5 minutes; however 82% did not have enough amount of sleep. 78% of patients had no feeling of dizziness during the day; 82% did not have shortness of breath; 80% reported that they slept without pain, while 41% reported that they did not sleep at all.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Author Biography

Hayriye Baltaoğlu Alp, Necmettin Erbakan University

Assist. Prof. Dr., Necmettin Erbakan University, Meram Faculty Of Medicine

References

Vgontzas AN, Chrousos GP. Sleep, The Hypothalamicpituitary- Adrenal Axis, and Cytokines: Multiple Interactions and Disturbances in Sleep Disorders. Endocrinol Metab Clin North Am 2002;31(1):15-36.

Palangio M, Northfelt DW, Portenoy RK ,et all.Dose Conversion and Titration with a Novel, Once-Daily, OROS® Osmotic technology, Extended-Release Hydromorphone Formulation in the Treatment of Chronic Malignant or Nonmalignant Pain. J Pain Symptom Manage.2002;23:355-368.

Resiine T,Pastemak G. Opioid Analgesics and Antagonists. In Hardman JG Limbird LE, Molinoff PB, eds. Goodmans ᵟ Gilmans The Pharmacological Basis of Therapeutics. 9th ed. Newyork ,NY: Mc Graw-Hill;1995:521-555

Sarhil N,Walsh D, Nelson KA Hydromorphone: Pharmacology and Clinicall Applications in Cancer Patients. Support Care Cancer .2001;9:84-96

Wallace M, Skowronski R,Khanna S, Tudor J,Thipphawong J. Efficacy and safety evaluation of Once-Daily OROS® Hydromorphone in Patients with Chronic Low Back Pain: A Pilot Open-Label Study Cun Med Res Opin. 2007;23P1-P9

Carla I,Ripamonti MD,Tiziana Campa MD,Elena Fagnoni MD, Normal-Release Oral Morphine Starting Dosen Cancer Patients with Pain Clin. J. Pain 2009;25:386-390

David Lussier,1'2 Ute Richarz3 and Gabriele Finco4 Use of Hydromorphone, with Particular Reference to the OROS® Formulation, in the Elderly DRUGS AGING

;27(4):327-335

Downloads

Additional Files

Published

2017-12-11

How to Cite

Baltaoğlu Alp, H. (2017). A study on cancer pain and sleep parameters of cancer patıents: Hydromorphone Hydrochloride. Journal of Human Sciences, 14(4), 4149–4154. Retrieved from https://j-humansciences.com/ojs/index.php/IJHS/article/view/4443

Issue

Vol. 14 No. 4 (2017)

Section

Medicine

License

Uluslararası İnsan Bilimleri Dergisi ISSN:1303-5134
International Journal of Human Sciences ISSN:2458-9489
 
is an "Open Access Journal" that uses a funding model that does not charge readers or their institutions for access. From the BOAI definition of open access, users take the right of read, download, copy, distribute, print, search, or link to the full texts of these articles.

Authors can retain copyright, while granting the journal right of first publication. Alternatively, authors can transfer copyright to the journal, which then permits authors non-commercial use of the work, including the right to place it in an open access archive. In addition, Creative Commons can be consulted for flexible copyright licenses.

©1999 Creative Commons Attribution-ShareAlike 4.0 International License.