Effects of secondary trimester maternal serum screening on the results of pregnancy

Authors

  • Kemal Dinç Istanbul Research and Education Hospital
  • Ramazan Ozyurt Istanbul Research and Education Hospital
  • Bulat Aytek Sık Istanbul Aydın University
  • Serkan Kumbasar Sakarya Research and Education Hospital
  • Yaşam Kemal Akpak Dışkapı Yıldırım Beyazıt Training and Research Hospital
  • Yılda Arzu Aba Bandirma Onyedi Eylul University

Keywords:

Serum scan test, alfa-fetoprotein, human chorionic gonadotropin, inhibin A, bad obstetric results

Abstract

In our study it was aimed to research the relations between pregnancy complications and frequencies of maternal and fetal complications which can be observed after the further follow-ups with biochemical indicators in gravid individuals whom found to be risky in quad test.120 patients who applied and had their labors conducted in İstanbul Training and Research Hospital and took quad test AFP (alpha fetoprotein), HCG (human chorionic gonadotropin), uE3 (unconjugated estriol), inhibin-A are included in our study. Conclusions planned to be obtained in this study are, IUGR (intrauterine growth deficiency), macrosomia, gestational diabetes, preeclampsia and preterm birth. 64 (% 53, 4) out of 120 patients participated in the study had normal labors while 56 (%46, 6) of the patients had labors with caesarean birth. On 70 (%58.3) patients whom did not develop obstetric complications, AFP value calculated as average as 1.00±0.74 MoM, uE3 value calculated as  0.89±0.4 MoM, hCg value calculated as 0.97±0.5 MoM and inhibin A value calculated as an average of  0.95±0.5 MoM.  On 50 (%41.6) patients whom developed obstetric complications, AFP value found as average of 1,06±0,74, uE3 value found as 0.96±0.39 MoM, hCG value found as 0.99±0.77 MoM and Inhibin A value found as 1.023±0.62 MoM. There were no significant deviation between the cases with obstetric complications and cases without obstetric complications in terms of AFP, uE3, HCG and Inhibin A values. There were no significant relation between threshold values of AFP, HCG, uE3 and inhibin A which are used in quad test as secondary trimester serum indicators in low risk populations and pregnancy complications.

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Author Biographies

Kemal Dinç, Istanbul Research and Education Hospital

Op. Dr. Department of Obstetrics and Gynecology, Istanbul Research and Education Hospital, Istanbul, Turkey

Ramazan Ozyurt, Istanbul Research and Education Hospital

Op. Dr. Department of Obstetrics and Gynecology, Istanbul Research and Education Hospital, Istanbul, Turkey

Bulat Aytek Sık, Istanbul Aydın University

Assistant Professor, Ph.D., Department of Obstetrics and Gynecology,  Istanbul Aydın University, Istanbul, Turkey

Serkan Kumbasar, Sakarya Research and Education Hospital

Op. Dr. Department of Obstetrics and Gynecology, Sakarya Research and Education Hospital, Sakarya, Turkey

Yaşam Kemal Akpak, Dışkapı Yıldırım Beyazıt Training and Research Hospital

Op. Dr. Department of Obstetrics and Gynecology, Dışkapı Yıldırım Beyazıt Training and Research Hospital

Yılda Arzu Aba, Bandirma Onyedi Eylul University

Assistant Professor, Ph.D., Bandirma Onyedi Eylul University, Health Science Faculty, Faculty of Health Science, Nursing Department, Balıkesir, Turkey

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Published

2017-11-24

How to Cite

Dinç, K., Ozyurt, R., Sık, B. A., Kumbasar, S., Akpak, Y. K., & Aba, Y. A. (2017). Effects of secondary trimester maternal serum screening on the results of pregnancy. Journal of Human Sciences, 14(4), 3653–3662. Retrieved from https://j-humansciences.com/ojs/index.php/IJHS/article/view/4806

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Section

Medicine